Final answer:
The nurse should advise the client to take calcium supplements two hours before taking the tetracycline antibiotic to ensure optimal absorption.
Step-by-step explanation:
The appropriate statement for the nurse to make is: Take your calcium two hours before you take the antibiotic. This is because tetracycline can form insoluble complexes with calcium, which can reduce the absorption of the antibiotic when taken together. By spacing the two medications apart, the client can maximize the absorption and effectiveness of the tetracycline.