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A patient has a serum study that is positive for the rheumatoid factor. What does the nurse understand is the significance of this test result?

a) Diagnostic for Sjögren's syndrome
b) Diagnostic for SLE
c) Specific for RA
d) Suggestive of RA

1 Answer

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Final answer:

The presence of rheumatoid factor is suggestive of rheumatoid arthritis but is not specific to it, as it can also be present in other autoimmune conditions. It is not diagnostic, and other tests and clinical symptoms are considered for a definitive diagnosis.

Step-by-step explanation:

The presence of rheumatoid factor (RF) in a patient's serum is commonly associated with rheumatoid arthritis (RA), but it is not specific only to this condition. RF is an antibody that can bind to the patient's own immunoglobulin G (IgG), and its presence is suggestive of RA but not conclusive. Therefore, the correct answer to the question of what the nurse understands the significance of this test result to be is d) Suggestive of RA.

While RF can be indicative of RA, it is not diagnostic as it can be present in other conditions such as Sjögren's syndrome, systemic lupus erythematosus (SLE), and other autoimmune diseases. In contrast, antinuclear antibody (ANA) tests are valuable in the diagnosis of SLE where autoantibodies against DNA or DNA-binding proteins can be present. For a definitive diagnosis, clinicians often rely on a combination of clinical symptoms and a range of laboratory tests.

User Gary Kerr
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