Answer:
4, "Thawed and refrozen"
Step-by-step explanation:
Large ice crystals in a case of frozen food are evidence that the product may have been thawed and refrozen. Therefore, option 4, "Thawed and refrozen," is the most appropriate choice in this scenario. This condition can affect the quality and safety of the frozen food, and it's generally recommended to avoid consuming products that show signs of thawing and refreezing.