Question

A client with severe peripheral artery disease (PAD) has been educated about the various growth factors and their functions. This client is hoping that the growth factor, fibroblast growth factor (FGF), will be able to repair the circulation to his lower extremities because this growth factor's function is to:

a) grow new vessels into the damaged area (angiogenesis).

b) increase vascular permeability.

c) stimulate replication of hepatocytes.

d) stimulate keratinocyte migration and the formation of granulation tissue.

Answer 1

Fibroblast growth factor (FGF) can aid in treating PAD by promoting angiogenesis, which is the growth of new vessels into damaged areas to restore circulation.

Step-by-step explanation:

A client with severe peripheral artery disease (PAD) is correct in hoping for the potential benefits of fibroblast growth factor (FGF) as it functions to grow new vessels into the damaged area (angiogenesis). FGF stimulates cell proliferation, cell migration and adhesion, and angiogenesis.

By promoting the growth of new blood vessels, FGF contributes to the restoration of circulation in areas where blood vessels have been compromised, which is essential in treating conditions like PAD