Final answer:
OPAs cannot be used in patients with an active gag reflex, presenting a significant disadvantage. Pediatric sizes are available, and using a lubricant is standard practice, not a disadvantage.
Step-by-step explanation:
Among the disadvantages of oropharyngeal airways (OPAs), one important drawback is that they cannot be used in a patient with a gag reflex. This is because the presence of an OPA can stimulate the gag reflex, which could lead to vomiting, aspiration, or injury in a semi-conscious or unconscious patient. It is also pertinent to note that pediatric sizes of OPAs are available, and while use of a water-soluble lubricant is advised for comfort and ease of insertion, this is not a disadvantage but a standard practice. Additionally, there is no direct contraindication for using OPAs in patients with suspected skull fractures, although careful assessment and monitoring is key in such scenarios.