Question

After synthesis of the skin what is converted to the liver and kidneys to calcitroil.

Answer 1

After vitamin D is synthesized in the skin, it is modified in the liver to calcidiol and then converted into the active form calcitriol in the kidneys, which is crucial for calcium and phosphorous absorption.

Step-by-step explanation:

After synthesis of vitamin D in the skin, it is converted in the liver and kidneys to the biologically active form, calcitriol. The epidermal layer of the skin synthesizes vitamin D3 or cholecalciferol when exposed to UV radiation from sunlight. This cholecalciferol enters the bloodstream and travels to the liver, where it is converted into calcidiol (25(OH)D).

This intermediate form of vitamin D is then transported to the kidneys, where it is further metabolized into 1,25(OH)D₂ (calcitriol), the active form of vitamin D essential for numerous bodily functions, including calcium and phosphorous absorption for healthy bones.