Question

In some cases the epiphyseal plate of the long bones of children closes too early. What might be the cause?

A) overproduction of thyroid hormone
B) osteoblast activity exceeds osteoclast activity
C) elevated levels of sex hormones

Answer 1

Elevated levels of sex hormones can cause premature closure of the epiphyseal plate in long bones, resulting in shorter stature.

Step-by-step explanation:

Premature closure of the epiphyseal plate in long bones of children can occur due to elevated levels of sex hormones. During puberty, sex hormones such as estrogen in girls and testosterone in boys promote osteoblastic activity and production of bone matrix. They also play a role in the conversion of the epiphyseal plate to the epiphyseal line, which stops longitudinal bone growth. This can lead to shorter stature in individuals with premature epiphyseal plate closure.