Final answer:
Defective NA+ channels, or channelopathies, can cause enhanced excitability and depolarization in neurons, leading to diseases such as epilepsy and cardiac arrhythmias. The option (B) is correct.
Step-by-step explanation:
Defective NA+ channels, also known as channelopathies, can result in enhanced excitability and depolarization in neurons.
When these channels are defective, they may allow an abnormal influx of sodium ions into the cell, leading to increased excitability and depolarization. This can contribute to various diseases and conditions, such as epilepsy and certain cardiac arrhythmias. Therefore, option (B) is correct.
This question is not complete, Here I am attaching the complete question:
Diseases associated with defective NA+ channels(channelopathies):
A) Increased channel activity leading to hyperpolarization
B) Enhanced excitability and depolarization
C) Decreased neuronal firing rates
D) Improved muscle contraction coordination