Final answer:
The treatment of ototoxicity and nephrotoxicity caused by cisplatin can be challenging and involves strategies like hydration and protective agents, since antibiotics like aminoglycosides themselves can be nephrotoxic and ototoxic.
Step-by-step explanation:
The treatment of ototoxicity and nephrotoxicity caused by cisplatin involves various approaches. Specific medications have been explored for these side effects, but a universally recognized treatment protocol is complex due to the varying individual patient responses and degrees of toxicity. The aminoglycosides, which are antibiotics like gentamicin, are known to be both nephrotoxic and ototoxic; therefore, they may not be suitable for managing cisplatin-induced toxicities. Instead, strategies to mitigate these side effects include adequate hydration, diuretic therapy to reduce nephrotoxic risk, and the use of other protective agents like amifostine. However, it's important to note that clinical judgment and patient monitoring remain essential to optimally manage these drug-induced side effects.