Final answer:
An open-ended question from the nurse encourages the client to clarify their medication adherence, aiding in effective management of their high blood pressure.
Step-by-step explanation:
The appropriate response for the nurse to make in response to the client's statement about not taking their high blood pressure medication as prescribed would be: "Tell me what you mean by not taking the medicine as prescribed." This open-ended question encourages the client to provide more information about their medication adherence, which can be crucial for managing their condition effectively.