Final answer:
The nurse should respond empathetically and supportively to the client's expression of sadness and frustration regarding their health condition.
Step-by-step explanation:
It is important for the nurse to respond to the client with empathy and understanding. Saying, "You're feeling upset about the news you got about the transplant" acknowledges the client's feelings and shows that the nurse is listening and validating their emotions. Taking a seat next to the client and sitting quietly allows for a peaceful and supportive presence, which can provide comfort to the client. Leaving the room to allow the client to collect their thoughts can also be an appropriate response, as it allows the client some privacy and space to process their feelings.