Final answer:
I-125 Glofil and creatinine are both radiopharmaceuticals used to measure the glomerular filtration rate (GFR), which is critical for monitoring kidney function and ensuring proper medication dosing.
Step-by-step explanation:
Two radiopharmaceuticals that can be used to measure the glomerular filtration rate (GFR) include I-125 Glofil and creatinine. Radiopharmaceuticals like these are essential tools for assessing kidney excretory function, which is vital for the proper dosing of medications that are excreted via urine. Inulin is another substance used to estimate GFR; it is a plant polysaccharide that is neither reabsorbed nor secreted by kidneys and appears in the urine in proportion to the filtration rate. However, due to the cumbersome nature of measuring inulin clearance, creatinine, which is a muscle metabolism product that is not reabsorbed and only slightly secreted by the nephron, is frequently used as a more convenient indicator of GFR in clinical settings.