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What chemokine attracts the naive T lymphocyte into the surrounding tissue and what receptor does it bind?

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Final answer:

Specific chemokines attract naive T lymphocytes to areas of inflammation or infection, and while the reference material does not name a particular chemokine, receptors like CCR7 are known to guide naive T cells in response to chemokines such as CCL19 and CCL21.

Step-by-step explanation:

The chemokine that attracts naive T lymphocytes into the surrounding tissue is a type of chemotactic cytokine whose function is to direct the migration of these cells to areas of inflammation or infection. Naive T cells express CD4 or CD8 molecules, which determine their interaction with antigen-presenting cells (APCs) and their role in the immune response. CD4+ T cells bind to MHC II molecules on APCs and differentiate into helper T cells (TH), while CD8+ T cells engage MHC I molecules and become cytotoxic T lymphocytes (CTLs). Both types of T cells require specific chemokines to move from the bloodstream into the surrounding tissue where infection or damage is present.

While the exact chemokine receptor involved was not provided in the reference material, it is established that chemokine receptors such as CCR7 on naive T cells are crucial for their trafficking to the lymph nodes in response to specific chemokines like CCL19 and CCL21.

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