Question

Acromegaly may be caused by all EXCEPT which of the following?

1) hypersecretion of GHRH (growth hormone-releasing hormone)
2) pancreatic tumor
3) lack of negative feedback by insulin-like growth factors
4)hyposecretion of GH in adulthood

Answer 1

Acromegaly in adults is caused by overproduction of GH and cannot result from the hyposecretion of GH in adulthood; thus, hyposecretion of GH is the exception in the given options.

Step-by-step explanation:

Acromegaly is a condition caused by the overproduction of growth hormone (GH) in adults. The causes of acromegaly include hypersecretion of GHRH (growth hormone-releasing hormone), a lack of negative feedback by insulin-like growth factors, and tumors of the pituitary gland. However, hyposecretion of GH in adulthood does not cause acromegaly, as the underproduction of GH in adults does not lead to abnormalities like those seen in acromegaly.

Therefore, hyposecretion of GH in adulthood is not a cause of acromegaly. While a pancreatic tumor can lead to endocrine system issues, such as diabetes, it is not directly related to the production of GH and is not a known cause of acromegaly.