Final answer:
True, premature thelarche can happen unilaterally or bilaterally. It is the early development of breast tissue before the typical age of puberty onset and may be benign or require further investigation by healthcare professionals.
Step-by-step explanation:
Premature thelarche is a condition marked by the early development of breast tissue in girls, typically before the age of 8. Thelarche refers to the onset of secondary breast development, which is usually one of the first signs of puberty. In premature thelarche, this development occurs earlier than expected and can be a normal variant or could be a sign of hormonal changes. It is important to differentiate premature thelarche from precocious puberty, where there is a more comprehensive development of secondary sexual characteristics.
The manifestation of premature thelarche can be unilateral, where breast development is seen in just one breast, or bilateral, where both breasts develop. If the thelarche is unilateral, it is particularly important for a healthcare provider to evaluate the child to rule out other conditions, like a cyst or a tumor. In the situation of bilateral premature thelarche, it is typically a benign condition and will often resolve on its own without treatment. While the exact cause of premature thelarche is not always known, it can sometimes be attributed to transient increases in estrogen production.
Management of premature thelarche involves monitoring to ensure no additional signs of puberty develop and to confirm that the growth pattern remains normal. Regular follow-ups with a pediatrician or a pediatric endocrinologist might be recommended to monitor the condition. In most cases, premature thelarche is a benign condition that does not have long-term consequences for the child's development or health.