Question

Describe what Tumor Lysis Syndrome is: Remember that purines get converted to what, which ultimately leads to what? High purine levels are known as? It can also come from what?

Answer 1

Tumor Lysis Syndrome (TLS) is a condition that occurs when cancer cells are destroyed rapidly, releasing their contents into the bloodstream. This can lead to several metabolic imbalances and complications. High levels of uric acid in the blood can cause kidney damage, electrolyte imbalances, and other health problems.

Step-by-step explanation:

Tumor Lysis Syndrome (TLS) is a condition that occurs when cancer cells are destroyed rapidly, releasing their contents into the bloodstream. This can lead to several metabolic imbalances and complications. When tumor cells break down, they release a large amount of nucleic acids, which are converted to purines and ultimately to uric acid. High levels of uric acid in the blood can cause kidney damage, electrolyte imbalances, and other health problems.

High levels of purines in the blood are known as hyperuricemia. TLS can occur as a result of cancer treatment, particularly chemotherapy or radiation therapy. The rapid destruction of tumor cells overwhelms the body's ability to eliminate uric acid, leading to its accumulation in the blood.