127k views
3 votes
How do we manage/prevent Tumor Lysis Syndrome?

User Tpdietz
by
8.3k points

1 Answer

7 votes

Final answer:

To manage or prevent Tumor Lysis Syndrome (TLS), hydration, medication, electrolyte monitoring and replacement, and kidney function monitoring are important measures.

Step-by-step explanation:

Tumor Lysis Syndrome (TLS) is a potentially life-threatening complication that can occur during cancer treatment. It is characterized by the rapid release of intracellular contents from dying cancer cells into the bloodstream, leading to metabolic imbalances. To manage or prevent TLS, several measures can be taken, including:

  • Hydration: Ensuring adequate fluid intake can help flush out the released substances and maintain hydration.
  • Allopurinol or rasburicase: These medications are used to lower uric acid levels, which can be elevated during TLS.
  • Electrolyte monitoring and replacement: Close monitoring of electrolyte levels and timely replacement can help maintain the balance of key electrolytes such as potassium, calcium, and phosphorus.
  • Close monitoring of kidney function: Regular assessment of kidney function is essential, and dialysis may be necessary in severe cases.

User Wasim Khan
by
8.3k points