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A patient in septic shock presents to the OR for an exploratory laparotomy. The induction rate of which of the following agents will be most affected by this clinical presentation?

A. Isofl urane
B. Desfl urane
C. Sevofl urane
D. Halothane
E. Nitrous oxide

User Evos
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1 Answer

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Final answer:

The induction rate of inhalational anesthetics, like halothane, which has a high blood/gas partition coefficient, may be most affected in a patient with septic shock due to compromised hemodynamics.

Step-by-step explanation:

A patient in septic shock presenting for an exploratory laparotomy will have altered physiology, which can impact the induction rate of inhalational anesthetics. The induction rate refers to how quickly a patient reaches an adequate level of anesthesia after administration of an agent.The induction rate of inhalational anesthetics can be influenced by factors such as blood flow and cardiac output, which are typically compromised in septic shock. The agent among the choices listed that will be most affected is likely to be halothane, due to its relatively high blood/gas partition coefficient, meaning that it has a slower induction and recovery rate, and its cardiovascular effects can be more pronounced in patients with compromised hemodynamics. Desflurane and sevoflurane, on the other hand, have low blood/gas partition coefficients, leading to more rapid induction and recovery. Nitrous oxide also has a low blood/gas partition coefficient and could be a preferable choice in these patients for maintaining anesthesia, although not for induction.

User Ivan BASART
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