Final answer:
Bisacodyl (Ducolax) is primarily indicated for treating opioid-induced constipation by stimulating bowel movements through the activation of adenylate cyclase, which leads to fluid secretion and bowel activity.
Step-by-step explanation:
Bisacodyl, commonly known by the brand name Ducolax, is a medication used to treat constipation. Its primary indication is for the relief of constipation caused by various factors, such as from lifestyle changes or certain medications. One of its uses is for opioid-induced constipation, which is a common side effect of opioid analgesics like morphine, codeine, oxycodone, and hydrocodone. Opioids relieve pain by acting on the central nervous system, but they can also decrease bowel movement by reducing the intestinal peristalsis. Bisacodyl works by stimulating bowel movement through the activation of adenylate cyclase in intestinal cells, leading to an increase in the levels of cyclic adenosine monophosphate (CAMP) which then prompts the secretion of fluids and electrolytes from the cells and induces bowel movements.