Final answer:
While (a) baldness, (b) headaches, (c) gastric irritation, and (d)orthostatic hypotension are possible side effects of androgen therapy, the most severe and irreversible effects include impaired heart function, testicular atrophy, and prostate enlargement, among other significant complications.
Step-by-step explanation:
When administering androgen therapy, a nurse should observe a client for several possible side effects. Although the choices a) Baldness, b) Headaches, c) Gastric irritation, and d) Orthostatic hypotension are listed, the most significant and concerning side effects of androgens include impaired heart function, testicular atrophy, and prostate enlargement.
These side effects can often be severe and irreversible. Additional possible complications related to androgen therapy may incorporate liver dysfunctions, prostate gland enlargement, difficulty urinating, premature closure of epiphyseal cartilages, infertility, and immune system depression, which can put a physiological strain on the body leading to heart attacks, strokes, and impaired cardiac function.