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Make each of the following choices that are associated with infectious mononucleosis. Splenomegaly develops in more than 50% of patients. Other clinical features may include hepatomegaly, jaundice, periorbital edema, soft palatal petechiae, generalized adenopathy, rubella-like rash, and a 30% co-incidence of streptococcal pharyngitis. The heart, lungs, lower gastrointestinal (GI) tract, and joints are rarely involved.

A. Splenomegaly
B. generalized adenopathy
C. lower gastrointestinal (GI) tract problems
D. posterior cervical lymphadenopathy
E. severe leukocytosis

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Final answer:

Associated with infectious mononucleosis are splenomegaly, generalized adenopathy, and posterior cervical lymphadenopathy. Severe leukocytosis is not usually a feature of infectious mononucleosis, and lower gastrointestinal tract problems are not commonly associated with this disease.

Step-by-step explanation:

Make each of the following choices that are associated with infectious mononucleosis (IM). The clinical features associated with IM often reflect widespread effects on the body's lymphatic system and may lead to several specific pathologies. The options given that are related to the clinical features of IM are:

  • Splenomegaly: A common finding in IM, occurring in more than half of patients and contributing to abdominal pain.
  • Generalized adenopathy: Reflects the lymph node swelling that is a hallmark of IM, indicating an immune response to infection.
  • Posterior cervical lymphadenopathy: Lymph node swelling, particularly in the neck region, is a common sign of IM.

While leukocytosis is typical in IM, severe leukocytosis would be outside the usual clinical presentation. Problems in the lower gastrointestinal (GI) tract are not a reported common feature of IM and are, therefore, not associated with this disease.

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