Final answer:
In science, a hypothesis is a tentative explanation and prediction based on observed evidence, which can be tested and refined.
Step-by-step explanation:
In science, a tentative explanation and prediction is known as a hypothesis. A hypothesis is an educated guess about how things work. It is a suggested solution that is based on evidence gathered through observation and experimentation. A scientist may use a hypothesis to predict the outcome of an experiment or as a guide for gathering and checking information. For instance, if someone is frequently sneezing in a house with a cat, the hypothesis might be that the individual is allergic to the cat's fur. This hypothesis can then be tested through further observation or experimental methods to see if it holds true. It's important to note that a hypothesis is very tentative and can be easily changed or refined as new evidence is collected.