Question

A therapeutic advantage of penicillin V over

penicillin G is
A. greater resistance to penicillinase.
B. broader antibacterial spectrum.
C. greater absorption when given orally.
D. slower renal excretion.
E. None of the above.

Answer 1

The therapeutic advantage of penicillin V over penicillin G is greater absorption when given orally, as penicillin V is stable in the stomach's acidic environment.

Step-by-step explanation:

The therapeutic advantage of penicillin V over penicillin G is its greater absorption when given orally. Penicillin G is unstable in the acidic environment of the stomach, leading to its inactivation, whereas penicillin V is acid-stable and can be effectively absorbed when given as an oral medication. This improved absorption makes penicillin V more suitable for oral administration, whereas penicillin G requires intravenous or intramuscular injection.