Final answer:
The preferred therapy for most nonfunctioning pituitary adenomas is transsphenoidal surgery, followed by radiation therapy if necessary.
Step-by-step explanation:
The preferred therapy for most nonfunctioning pituitary adenomas is transsphenoidal surgery. Transsphenoidal surgery involves removing the tumor through the nose or mouth to gain access to the pituitary gland. This approach allows for direct visualization and removal of the tumor with minimal damage to surrounding structures.
In some cases, radiation therapy may also be used after surgery to target any remaining tumor cells and prevent regrowth.
Medical management options, such as hormone replacement therapy, may be needed if the surgery or radiation does not fully normalize hormone levels.