Question

Parkinson disease is a progressive loss of motor function due to the degeneration of specific neurons. These neurons secrete an inhibitory neurotransmitter that prevents excessive activity in motor centers of the brain. This neurotransmitter is

a) serotonin.
b) dopamine.
c) acetylcholine.
d) GABA (.-aminobutyric acid).
e) glutamate (glutamic acid

Answer 1

Parkinson's disease involves the loss of dopamine-producing neurons in the substantia nigra, leading to motor and non-motor symptoms. correct answer is B.

Step-by-step explanation:

Parkinson's disease is characterized by the progressive degeneration of neurons that release dopamine, which is crucial for controlling muscle movement. As these neurons die, individuals experience symptoms such as tremors, slowed movement, and muscular rigidity. The loss of dopamine-producing neurons occurs in the substantia nigra, part of the midbrain, leading to difficulties in movement and coordination.

Despite ongoing research, the exact cause of neuron degeneration in Parkinson's disease is not fully understood. However, genetic and environmental factors along with mitochondrial dysfunction, oxidative stress, and possibly glutamate excitotoxicity, contribute to the condition. The most common treatment is aimed at replacing or mimicking dopamine through the administration of L-DOPA, the precursor to dopamine, which helps alleviate symptoms temporarily.