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Why must there be only 23 chromosomes and ONE member from each homologous pair in each of the gametes?

What are the potential effects of any difference in the number?

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Final answer:

Gametes carry only 23 chromosomes to ensure that upon fertilization the offspring has the correct number of 46 chromosomes. A deviation can lead to disorders or infertility. The random assortment and crossover in meiosis result in high genetic diversity.

Step-by-step explanation:

Understanding Chromosome Distribution in Gametes

In humans, normal cells have 46 chromosomes, which are organized into 23 pairs. These pairs consist of homologous chromosomes with the same genes, though they may carry different alleles. During meiosis, a process of cell division specific to gamete formation (sperm and eggs), these homologous pairs are separated such that each gamete ends up with only 23 chromosomes or one member from each homologous pair.

This segregation into gametes is crucial for maintaining the correct number of chromosomes in the offspring. When the sperm and egg come together during fertilization, they restore the diploid number of chromosomes (46), ensuring the offspring has the right genetic content. Any deviation from the normal number, an event called aneuploidy, can lead to various developmental disorders, such as Down syndrome, which is caused by an extra copy of chromosome 21, or infertility.

The potential for variation in the next generation is huge due to the random assortment of homologous chromosomes during meiosis. For humans, this results in over eight million possible chromosomal combinations in each gamete, which is before considering additional genetic diversity introduced by crossover events. These mechanisms ensure a vast pool of genetic diversity in offspring, key for the survival and evolution of a species.

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