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Where in the body do we find type I, II, and IV collagens?

User Ritu
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Final answer:

Type I collagen is found in skin, bone, tendons, and fibrous cartilage; Type II collagen is located in cartilage, such as joints, rib cage, and ears; Type IV collagen is in the basal lamina of the epithelial layer in skin, lungs, and blood vessels.

Step-by-step explanation:

Collagen Types and Their Locations

Collagen is a primary structural protein found in various connective tissues throughout the body. The different types of collagen serve specific purposes and are distributed in distinct areas.

  • Type I Collagen is the most abundant form, found in connective tissues like skin, bone, tendons, fibrous cartilage, and dentin.
  • Type II Collagen is mainly located in cartilage, including hyaline cartilage and elastic cartilage, which are found in joints, the rib cage, the nose, and the ear.
  • Type IV Collagen forms a network and is present in the basal lamina, or basement membrane, which is part of the epithelial layer found in the skin, lung, and blood vessels.

These collagen types contribute to the integrity and physical properties of tissues where they are found. For instance, fibrous connective tissue comprising predominantly Type I collagen provides strength to areas like tendons and ligaments. Type II collagen gives cartilage its compressive strength, and Type IV supports the structure of tissues at microscopic levels.

User Fraser Graham
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