Final answer:
The key difference between Old and New World food production was the lack of significant animal domestication in the New World before European contact.
Step-by-step explanation:
The most significant contrast between Old and New World food production was the little or lack of animal domestication in the New World (Option B). Unlike the Old World, where the rise of agriculture led to the domestication of animals such as sheep, goats, and horses, the New World did not have a large number of animals suitable for domestication prior to the European introduction of species like horses and cows. The domestication of animals in various regions enabled societies to build a surplus of goods through breeding livestock for food, clothing, and transportation, which also led to the development of specialized occupations and trading with other groups.