Final answer:
The globular protein THYROGLOBULIN combines with iodine ions to make THYROID HORMONE in the thyroid gland.
Step-by-step explanation:
In the thyroid gland, the globular protein THYROGLOBULIN combines with iodine ions to make THYROID HORMONE. Thyroglobulin is present in the follicles of the thyroid and is converted into thyroid hormones, T3 and T4, with the addition of iodine. T4 contains four iodine ions, while T3 contains three iodine ions. T3 is more active than T4 and is responsible for most of the effects of thyroid hormones.