Final answer:
The best synonym for Artifact is 'relic,' which refers to an ancient or historical object made by humans, aligning with the broad definition of an artifact as any human-made object.
Step-by-step explanation:
The best synonym for Artifact as presented in the options would be E) relic. This is because, as defined by various sources including the Oxford English Dictionary and engineering vocabulary, an artifact is an object made by human beings. It could range from the simplest of tools to the most intricate of designs, all categorized as artifacts due to their human origin. A relic generally refers to an old, historical object that has survived from the past, which fits into the broader definition of an artifact. It implies something ancient or of some significance, similar to how the term artifact is used, especially in archaeology. This distinguishes it from a poem, a skill, or a statement which do not denote a physical object made by people.