Final answer:
"Doomed" cells survive (Cells that should be apoptosing do not) this can happen due to mutations, loss of receptors, or overexpression of growth factor pathways. In cancer, failure of apoptosis can lead to uncontrolled cell division.
Step-by-step explanation:
Apoptosis, or programmed cell death, is a natural process in which damaged, superfluous, or potentially dangerous cells are eliminated by the body. However, sometimes these cells do not undergo apoptosis as they should, leading to their survival. This can occur due to various reasons, including mutations that prevent the initiation of apoptosis signaling, loss of expression of the receptor for the apoptosis-inducing ligand, or overexpression of a growth factor pathway that inhibits apoptosis.
In the context of cancer, failure of cells to undergo apoptosis can contribute to uncontrolled cell division and the formation of tumors. Therefore apoptosis is a programmed cell death process that eliminates damaged or dangerous cells. However, sometimes cells that should undergo apoptosis survive. This can happen due to mutations, loss of receptors, or overexpression of growth factor pathways. In cancer, failure of apoptosis can lead to uncontrolled cell division.