Final answer:
The hopes of the Ghost Dance were destroyed by the Wounded Knee Massacre, where the U.S. cavalry massacred hundreds of Lakota men, women, and children.
Step-by-step explanation:
The hopes of the Ghost Dance were destroyed by several events. One significant event was the Wounded Knee Massacre in 1890. The Lakota people were performing the Ghost Dance on their reservation, which led to fears among white settlers of another uprising. The U.S. cavalry rounded up the Ghost Dancers, and when they caught up to them at Wounded Knee, a rifle discharge led the troops to open fire indiscriminately, resulting in the massacre of approximately 150-300 Lakota men, women, and children.