Final answer:
During first pass metabolism, alcohol is metabolized in the liver by alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) enzymes. ADH converts alcohol into acetaldehyde, which is further metabolized into acetate by ALDH. This process produces NADH, a reduced coenzyme.
Step-by-step explanation:
During first pass metabolism, alcohol is metabolized in the liver through a series of reactions. The primary enzyme involved in this process is alcohol dehydrogenase (ADH), which converts alcohol (ethanol) into acetaldehyde. Acetaldehyde is then further metabolized by acetaldehyde dehydrogenase (ALDH) into acetate, a non-toxic molecule. This process also generates NADH, a reduced form of a coenzyme that carries electrons.