Question

____ drugs require a carrier enzyme or protein to pass through the GI membrane

Answer 1

Carrier-mediated drugs require a carrier enzyme or protein to pass through the GI membrane. One example is the use of peptide transporters in prodrug design to enhance drug absorption.

Step-by-step explanation:

Drugs that require a carrier enzyme or protein to pass through the GI membrane are known as carrier-mediated drugs. These drugs use specific transport proteins or enzymes to facilitate their absorption into the body. One example of this is the use of peptide transporters in prodrug design, where a specific amino acid is conjugated with a drug to enhance its absorption through the di- and tripeptide transporter (hPepT1) expressed in intestinal cells.