Question

If a drug has a half-life of 12 hours and is given twice daily starting at 0800 on a Monday, when will a steady state be achieved? TestBankWorld.org a. 0800 on Tuesday b. 0800 on Wednesday c. 0800 on Thursday d. 0800 on Friday

Answer 1

Steady state will be achieved at 0800 on Thursday.

Step-by-step explanation:

To determine when steady state will be achieved, we need to consider the concept of half-life. The half-life of a drug is the time it takes for half of the drug to be eliminated from the body. In this case, the drug has a half-life of 12 hours. If the drug is given twice daily, it means that every 12 hours, another dose is introduced into the body. Steady state is typically achieved after five half-lives, which in this case would be
`5 * 12 = 60` hours. Starting at 0800 on a Monday, 60 hours later is 2000 on a Wednesday. Therefore, the correct answer is 0800 on Thursday (c).