Final answer:
Neuropathy is a complication of diabetes.
Step-by-step explanation:
The statement that is true regarding systemic complications of diabetes is: B. Neuropathy is a complication of diabetes. Diabetic neuropathy is a common and serious complication of diabetes that affects the nerves in the extremities, causing symptoms such as numbness, tingling, and pain. It can also lead to problems with balance and coordination. The correct statement regarding systemic complications of diabetes is that neuropathy is a complication of diabetes, and gangrene can occur in peripheral extremities if diabetes is uncontrolled. Therefore, the true statement among the options given is E. Both B and C are true. Neuropathy may manifest as numbness, tingling, and pain in the extremities. Uncontrolled diabetes can lead to serious complications, including blood vessel damage that reduces circulation, increasing the risk of gangrene, and many other systemic complications.