Final answer:
The client's statement about taking antacid due to indigestion while on naproxen requires further discussion as it may indicate gastrointestinal side effects, a common concern with NSAID use.
Step-by-step explanation:
The client's statement that requires further discussion by the nurse is "I've been taking an antacid to help with indigestion." Naproxen is a Nonsteroidal Anti-inflammatory Drug (NSAID) that can potentially cause gastrointestinal side effects, including ulcers and gastrointestinal bleeding. The use of antacids may indicate that the client is experiencing gastrointestinal discomfort, which could be an adverse effect of naproxen. The nurse should discuss this symptom with the client to assess for possible gastrointestinal ulcers or irritation and provide appropriate care or guidance. Crushing the medication, as mentioned in option D, could possibly alter its effectiveness and also warrants further discussion; however, it is the antacid use in the context of NSAID-induced gastrointestinal symptoms that is generally more concerning.