Final answer:
The nurse should advise the patient to take colchicine with food if nausea occurs and to monitor for muscle pain, as colchicine can cause muscle weakness or pain. It's also important to note that grapefruit juice should be avoided due to potential interaction with the medication.
Step-by-step explanation:
The nurse should include the following instructions when teaching a client who has a new prescription for colchicine to treat gout: "Take this medication with food if nausea develops." This advice helps manage potential gastrointestinal side effects like nausea. Additionally, the nurse should instruct the patient to "Monitor for muscle pain" as colchicine can cause muscle weakness or pain as a side effect. It's important to note that colchicine does not increase inflammation; rather, it decreases it by inhibiting mitosis. Finally, the nurse should not advise an increase in the intake of grapefruit juice as it can interact with many medications, including colchicine, potentially leading to adverse effects.