Final answer:
Bisphosphonates are the indicated agent for the treatment of Paget's disease of the bone. They help reduce the risk of fractures and deformities associated with the disease, although they may also have a small risk of increasing fractures in some cases.
Step-by-step explanation:
The agent indicated for the treatment of Paget's disease of the bone is bisphosphonates. Bisphosphonates are drugs that decrease the activity of osteoclasts, which helps to reduce the overall risk of fractures and deformities associated with Paget's disease. However, it is important to note that in a small percentage of cases, bisphosphonates themselves have been linked to an increased risk of fractures. Therefore, the benefits and risks of bisphosphonate treatment should be assessed on a case-by-case basis by a medical professional.