Final answer:
Emphysema is a chronic lung disease where the inner walls of the alveoli are damaged due to smoking, leading to impaired gas exchange and an inability to fully expel air from the lungs, resulting in symptoms like shortness of breath and chronic cough.
Step-by-step explanation:
Emphysema Definition
Emphysema is a chronic lung disease primarily caused by smoking, where there is damage to the alveoli which impairs the gas exchange. This condition is a type of chronic obstructive pulmonary disease (COPD), a group of lung diseases that block airflow and make it difficult to breathe.
Pathophysiology of Emphysema
In emphysema, the inner walls of the alveoli are damaged, leading to a decreased surface area for gas exchange. The loss of lung tissue elasticity results in air trapping and reduced lung recoil, causing difficulty in expelling air from the lungs. Over time, these changes can lead to increased airway resistance and cause symptoms such as shortness of breath and chronic cough. Unfortunately, emphysema-induced damage is irreversible.
Factors Contributing to Emphysema
Smoking is the leading cause of emphysema as it contributes to the breakdown of alveolar walls and loss of their elastic fibers. Exposure to certain toxins and genetic factors can also increase the risk of developing emphysema.