Final answer:
Tolerance is the term for the drug effect that occurs when the amount of drug given is greater than the rate at which it is being excreted. It develops when the body becomes less responsive to a drug, requiring higher doses to achieve the same effect.
Step-by-step explanation:
The term for the drug effect that occurs when the amount of drug given is greater than the rate at which it is being excreted is tolerance. Tolerance develops when the body becomes less responsive to a drug, requiring higher doses to achieve the same effect. This can happen due to a variety of reasons, such as increased enzyme activity that metabolizes the drug or increased expression of drug transporters that eliminate the drug from the body.