Final answer:
For SLE with nephropathy, the next steps include renal function tests and monitoring with full blood count, urinalysis, ANA with Sm, and calcium levels, potentially followed by kidney biopsy based on the severity.
Step-by-step explanation:
The next step for a patient with Systemic Lupus Erythematosus (SLE) presenting with newly found nephropathy and an increased creatinine level is to conduct a renal function test and possibly a kidney biopsy. To monitor the situation, tests such as full blood count (FBC), urinalysis, and antinuclear antibody test (ANA), specifically with attention to Smith antigen (Sm), should be carried out. Additionally, measuring blood calcium levels and keeping track of urine output are essential.
As the patient's kidney function decreases, there may be challenges such as acute renal failure. Monitoring the renal function is crucial in managing lupus nephritis. It is vital to track the serum creatinine levels and urine output and assess for any other renal damage indicators like proteinuria and hematuria.
Further management can include immunosuppressive therapy, blood pressure control, and preventing further kidney damage. Coordination with a rheumatologist and a nephrologist is critical in providing the right care for patients with lupus nephritis.