Final answer:
Allergic bronchopulmonary aspergillosis (ABPA) is an immune reaction caused by the inhalation of Aspergillus spores. Treatment involves antifungal agents and corticosteroids to target the fungal infection and manage allergic symptoms.
Step-by-step explanation:
Allergic bronchopulmonary aspergillosis (ABPA) is an immune reaction caused by the inhalation of Aspergillus spores. It is a type III hypersensitivity reaction where immune complexes are formed in the lungs, leading to inflammation and damage. The immune response involves the activation of eosinophils, T cells, and the release of cytokines. Treatment for ABPA includes antifungal agents such as itraconazole and voriconazole to target the fungal infection. Corticosteroids are also used to manage allergic symptoms by reducing inflammation. However, in disseminated infections, corticosteroids need to be discontinued to allow the immune system to mount a response.