Final answer:
Mixed cryoglobulinemia syndrome, distinct from SLE, is characterized by immune complexes and specific organ involvement, diagnosed via cryoglobulins detection and treated by addressing underlying causes and immunosuppression.
Step-by-step explanation:
The symptoms of mixed cryoglobulinemia syndrome can often be confused with those of other disorders, such as Systemic Lupus Erythematosus (SLE), because both involve type III hypersensitivity reactions. However, the presence of mixed cryoglobulins is specific to mixed cryoglobulinemia syndrome, not SLE.
In mixed cryoglobulinemia syndrome, symptoms may include skin ulcers, arthralgias, weakness, renal impairment, and neuropathy. The laboratory tests for diagnosing mixed cryoglobulinemia syndrome include the detection of cryoglobulins in the serum. Treatment typically involves addressing the underlying cause if known (such as hepatitis C), immunosuppressive therapy, and in some cases, plasmapheresis.