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Pt w/RUQ pain, elevated bili, elevated LFTs + IVDA hx. What test to do?

User Tida
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Final answer:

The patient should undergo a series of diagnostic tests including liver function tests (LFTs), complete blood count (CBC), ultrasound, abdominal CT scan, HIDA scan, and possibly endoscopic ultrasound, as well as specific tests to check amylase or lipase levels and serologies for hepatitis, given their history of IVDA and presentation of symptoms.

Step-by-step explanation:

Appropriate Tests for RUQ Pain, Elevated Bilirubin, Elevated LFTs, and History of IVDA

The clinical scenario of a patient presenting with right upper quadrant (RUQ) pain, elevated bilirubin levels, elevated liver function tests (LFTs), and a history of intravenous drug use (IVDA) suggests possible hepatobiliary or pancreatic pathology, which may include hepatitis, cholangitis, or pancreatitis secondary to IVDA-related complications or other causes.


To diagnose the specific cause of these symptoms, a series of tests should be conducted.

  • Liver function tests (LFTs): These are essential initial tests that assess the health of the liver and can indicate the presence of gallbladder disease.

  • Complete blood count (CBC): This test can identify if there is an infection present due to a high white blood cell count.

  • Ultrasound: This non-invasive test uses sound waves to create images of the abdominal organs and can detect gallstones, biliary tract obstruction, or other abnormalities in the liver and pancreas.

  • Abdominal CT scan: For a more detailed imaging, this scan may reveal further details not seen on ultrasound, including abscesses or pancreatic pathology.

  • HIDA scan: This special imaging test evaluates the function of the gallbladder and bile ducts using a radioactive tracer.

  • Other tests such as the amylase or lipase levels should be checked to investigate for pancreatic inflammation.

  • Endoscopic ultrasound may be indicated for a more detailed view of the pancreas and surrounding structures.

With the clinical picture of obstructive jaundice and a history of IVDA, it is crucial to consider infectious causes such as viral hepatitis, which could be investigated with appropriate serologies. It is also important to consider liver injury secondary to illicit drug use, which may require specific toxicological screening.

User Hamid Narikkoden
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