Final answer:
Blocking the Na-glucose cotransporter 2 can lead to increased urination, possible dehydration, changes in blood pressure and heart rate, and gastrointestinal issues such as nausea, diarrhea, and vomiting.
Step-by-step explanation:
The common complication of blocking the Na-glucose cotransporter 2 (SGLT2) is an increase in the frequency of urination due to the drug's effect on the kidneys. When SGLT2 is inhibited, less glucose is reabsorbed by the kidneys, leading to more glucose being excreted in the urine. This mechanism helps to lower blood glucose levels in diabetic patients but can lead to possible dehydration and changes in blood pressure and heart rate due to the increased loss of water and electrolytes.
Other side effects may include nausea, diarrhea, and vomiting which can last between 24-48 hours. It’s important for patients taking SGLT2 inhibitors to be aware of these potential complications to manage them effectively with the help of their healthcare provider.