Final answer:
Notify the healthcare provider if the patient develops yellow-tinged skin, changes in hearing, or orange-colored sputum.
Step-by-step explanation:
When teaching the patient receiving standard multidrug therapy for tuberculosis (TB) about possible toxic effects of the antitubercular medications, the nurse should instruct the patient to notify the health care provider if they develop yellow-tinged skin, changes in hearing, or orange-colored sputum.
Yellow-tinged skin can indicate liver toxicity, which is a possible side effect of the antitubercular medications. Changes in hearing can suggest ototoxicity, another potential side effect. And orange-colored sputum can be a sign of drug-induced hepatotoxicity.
It is important for the patient to promptly report these changes to their health care provider so that appropriate action can be taken to manage the toxic effects and adjust the medication regimen if necessary.