Final answer:
To assess a male for hypogonadism before prescribing TRT, serum testosterone levels should be drawn in the morning as testosterone levels are highest at that time. It is important to measure both total and free testosterone levels, as well as other hormone levels, to get a comprehensive assessment of the patient's hormonal profile.
Step-by-step explanation:
When assessing a male for hypogonadism prior to prescribing TRT (testosterone replacement therapy), serum testosterone levels should be drawn in the morning, as this is when testosterone levels are typically highest. A fasting sample is preferred, as eating can temporarily increase testosterone levels. It is important to measure both total testosterone and free testosterone levels, as well as other hormone levels such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH), to get a comprehensive assessment of the patient's hormonal profile. These tests help determine if the patient's testosterone levels are indeed low and if TRT is appropriate.