Final answer:
Ciprofloxacin would be an appropriate first-line antibiotic for a 24-year-old female with a urinary tract infection and a sulfa allergy. It is effective and doesn't belong to the sulfonamide class, thus avoiding allergic reactions.
Step-by-step explanation:
The student's question regarding an appropriate first-line antibiotic for a 24-year-old female with a urinary tract infection (UTI) and a sulfa allergy involves a knowledge of common UTI pathogens and appropriate antibiotics. An ideal choice for this scenario would be D. Ciprofloxacin, as it is effective against a broad range of bacteria commonly causing UTIs, including E. coli, and is not related to sulfonamide antibiotics, which the patient is allergic to. Trimethoprim/sulfamethoxazole should be avoided due to the patient's sulfa allergy. Azithromycin is generally not used as a first-line treatment for UTIs, and Ceftriaxone might be considered more for complicated UTIs or inpatient treatment.