Question

A 33 year-old presents with sinusitis unresponsive to three various antibiotics over the past four months. Sinus puncture is performed with culture positive for Aspergillus fumigatus. What is the most appropriate treatment for this patient?

A. Amphotericin (Amphotericin B)
B. Amoxicillin/Clavulanate (Augmentin)
C. Ofloxacin (Floxin)
D. Cefuroxime (Ceftin

Answer 1

Amphotericin B (Amphotericin B) is the most appropriate treatment for a patient with sinusitis caused by Aspergillus fumigatus, as it is a broad-spectrum antifungal medication effective against such infections.

Step-by-step explanation:

The case describes a 33-year-old patient with sinusitis caused by Aspergillus fumigatus, which is unresponsive to antibiotic treatment. This is an indication of a fungal infection rather than a bacterial one, and therefore requires antifungal treatment.

\The most appropriate choice for treating aspergillosis, as indicated by the culture positive for Aspergillus fumigatus, would be Amphotericin B (Amphotericin B). This option is supported by literature that identifies Amphotericin B as a broad-spectrum antifungal drug usually utilized for treating such invasive fungal infections.